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Some are, including GLP-1 receptor agonists (semaglutide, tirzepatide), insulin, and a range of hormone-based therapeutics

The described methodologies are broadly applicable and adaptable to Fabry disease involving diverse tissues, including the heart, brain, and skin, and can be used immediately to experimentally investigate molecular pathways and novel treatments

This is because NNMTi improves fat metabolism to assist weight loss, alleviates intestinal inflammation, and reduces gastrointestinal adverse reactions.These combined intervention studies provide novel strategies for clinical obesity management and expand the application scope of NNMTi

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